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Name: tirzepatide surmount-1 trial nejm 2022 weight loss results tirzepatide surmount 5 SURMOUNT-1 (NEJM 2022) tested tirzepatide — a dual GIP/GLP-1 receptor agonist — in 2,539 adults with obesity and achieved up to 20.9% mean weight loss at the highest dose. 57% of participants
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Tirzepatide and Cardiovascular Outcomes: A Narrative Review of Mechanisms, Efficacy and Implications for Heart Failure Management - AbdulHafez - 2026 - Endocrinology, Diabetes & Metabolism - Wiley Online Library

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